bFGF (basic Fibrolast Growth Factor)

PRODUCT NAME:
• bFGF

INCI NAME:
• sh-polypeptide-1

WEIGHT:
• 5kg

ORIGIN:
• South Korea

INTRODUCTION:
• bFGF activates key signaling pathways in cells: MAPK/ERK (regulating proliferation and differentiation), PI3K/AKT (enhancing cell survival), and PLCγ (controlling cell migration and angiogenesis).
• As a result, bFGF promotes the biochemical synthesis processes of cells; specifically stimulating fibroblast growth, leading to increased collagen and elastin production, and the formation of new blood vessels, contributing to effective tissue regeneration and repair.
=> bFGF is the golden key for a product that aids in repair, anti-aging, and wound healing.

MARKETING POINTS:
• High biological activity
• Stimulates fibroblast growth, the cells responsible for producing Collagen and Elastin
• Helps firm and elastically restore the skin, improve skin texture, and reduce scars and wrinkles
• Dosage: 1%

QUALITATIVE AND QUANTITATIVE ANALYSIS:
• Keyprogen bFGF is a high-purity product (97% ±3)
• SDS-PAGE experiments show a consistent molecular quantity

BIOLOGICAL ACTIVITY ANALYSIS OF bFGF:
• For Keyprogen bFGF, the ED50 value (ED50: Effective dose for 50% of the test sample) is 0.25ng/ml compared to PEPROTECH bFGF, used as a standard. The specific activity of Keyprogen bFGF is 3.8*10^6 IU/mg.

WOUND HEALING AND SKIN REGENERATION:
• Wound healing ability using bFGF at 0.3ng compared to the control group: bFGF heals the wound in just 48 hours, with the wound size reduced to about a quarter of that in the control group.

• Cell migration activity test: Using 10ng of bFGF, the cell migration ability is doubled compared to the control group, which also means that the rate of tissue repair is accelerated.

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