PrzvFree 4HAP/Hydroxyacetophenone
PrzvFree 4HAP – Hydroxyacetophenone Antioxidant, Soothing and Preservation Support Ingredient
✔ PrzvFree 4HAP is an ingredient with the INCI name Hydroxyacetophenone, developed as a multifunctional cosmetic ingredient with key functions including antioxidant activity, skin soothing and broad-spectrum antimicrobial activity.
✔ Hydroxyacetophenone is also used as a skin-conditioning ingredient and can help enhance the preservation system in cosmetic formulations.
1. What is PrzvFree 4HAP?
✔ Hydroxyacetophenone can exist in several isomeric forms, including 4-Hydroxyacetophenone (p-hydroxyacetophenone, piceol), a phenolic compound found in the needles and mycorrhizal roots of Norway spruce (Picea abies).
✔ PrzvFree 4HAP uses Hydroxyacetophenone as its main ingredient and is positioned as a multifunctional raw material combining antioxidant, soothing and microbial-control supporting properties in cosmetic formulations.
2. Basic Information of PrzvFree 4HAP
✔ Trade Name: PrzvFree 4HAP
✔ INCI Name: Hydroxyacetophenone
✔ Origin: China
✔ CAS No.: 99-93-4
✔ Appearance: White to off-white crystalline solid
✔ Recommended Use Level: 0.3–1.0%
✔ Packaging: 25 kg, 500 kg
3. Key Features of PrzvFree 4HAP
3.1. Antioxidant Activity
✔ The antioxidant activity of PrzvFree 4HAP was evaluated using the DPPH free-radical scavenging test.
✔ The test was performed at concentrations of 10 mg/mL and 100 mg/mL, corresponding to approximately 1% and 10%.
=> Results:
• PrzvFree 4HAP demonstrated clear antioxidant activity.
• At 100 mg/mL, its antioxidant activity reached approximately 20–25%.
3.2. Broad-Spectrum Antimicrobial Activity
✔ A Minimum Inhibitory Concentration (MIC) test was conducted against five microorganisms, including:
Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans and Aspergillus niger.
✔ In the test, PrzvFree 4HAP at 0.3% demonstrated antimicrobial activity against the evaluated bacteria, yeast and mold.
Conclusion: PrzvFree 4HAP showed broad-spectrum antimicrobial activity, with performance comparable to Caprylyl Glycol and superior to Phenoxyethanol under the test conditions.
This is one of the key characteristics supporting the use of PrzvFree 4HAP as an ingredient to enhance the preservation system.
3.3. Supports the Preservation System
✔ Hydroxyacetophenone can enhance the preservation system in cosmetic formulations. This may allow formulators to reduce the level of certain preservatives, such as Phenoxyethanol, while still aiming to maintain preservation efficacy.
✔ Therefore, PrzvFree 4HAP can be used as a preservation booster, rather than functioning solely as an antioxidant ingredient.
3.4. Supports Skin Soothing
✔ Hydroxyacetophenone has skin-soothing properties, with a mechanism associated with the inhibition of COX-2 enzyme activity on the skin surface, an enzyme that may be related to signs of irritation.
✔ Therefore, PrzvFree 4HAP can be suitable for formulations requiring a combination of antioxidant activity, preservation support and soothing properties.
4. Compatibility with Polyol Systems
✔ Another advantage of PrzvFree 4HAP is its good compatibility with polyol systems.
✔ A stability test of 1.0% PrzvFree 4HAP in Propylene Glycol showed that after 3 months:
• No sediment was observed
• No color change was observed
• The solution maintained good stability
✔ Therefore, Propylene Glycol is recommended as a suitable solvent for incorporating PrzvFree 4HAP into various types of cosmetic formulations.
5. Application Guide for PrzvFree 4HAP
✔ In emulsion formulations:
• Disperse PrzvFree 4HAP in Propylene Glycol, then add it to the formulation and homogenize until the system is completely uniform. The ingredient can be used in both cold-process formulations and high-temperature processes up to ≤90°C.
✔ In anhydrous formulations:
• Propylene Glycol is a suitable solvent for PrzvFree 4HAP, helping dissolve and incorporate the ingredient into water-free systems.
✔ In water-based formulations:
• It is recommended to use Propylene Glycol or other diols in combination with a solubilizer, such as PEG-40 Hydrogenated Castor Oil, to support the dispersion/solubilization of PrzvFree 4HAP in the aqueous system.
6. Storage of PrzvFree 4HAP
✔ Store the ingredient in a cool, dry and well-ventilated place, and keep the container tightly closed.
PrzvFree 4HAP – A Multifunctional Ingredient for Modern Cosmetic Formulations
✔ By combining antioxidant activity, skin-soothing properties, broad-spectrum antimicrobial activity and preservation-system support, PrzvFree® 4HAP provides multiple benefits within a single ingredient.
Contact 3H Cosmetic to receive the TDS, samples and formulation support for PrzvFree 4HAP.
📞 Hotline: 032 761 2525
