Geozyme™ Enzyme
Geozyme™ Enzyme – AI-Powered Smart Screening – A Breakthrough in Synthetic Biotechnology – Unlocking a Brighter Smile
• Geozyme™ Enzyme (INCI Name: Glycerin & Water & 1,2-Pentanediol & 1,2-Hexanediol & Protease & Ethylhexylglycerin) is a bio-cleaning enzyme developed with AI technology, capable of breaking down protein stains at the molecular level to support safe, non-abrasive teeth whitening.
1. What is Geozyme™ Enzyme? A New Generation of Non-Abrasive Enzymatic Tooth Cleaning Solution
• Geozyme™ Enzyme is a next-generation oral care enzyme ingredient developed using advanced biotechnology to degrade protein-based stains on teeth at the molecular level, replacing traditional abrasive whitening mechanisms.
• Unlike conventional whitening agents that only act on the tooth surface, Geozyme™ functions as a “smart biological enzyme,” safely and effectively removing protein stains — one of the main causes of tooth discoloration.
2. Biotechnology Derived from Extremophile Microorganisms
• Geozyme™ is developed from fermented extremophile microorganisms isolated from the Quzhuomu hot springs in Tibet — an extreme environment that enables the enzyme to possess:
• High stability under harsh conditions
• Sustainable performance across multiple formulation systems
• Outstanding bio-cleaning efficiency
👉 This serves as the foundation that makes Geozyme™ a high-performance oral care enzyme ingredient.
3. AI-Based Enzyme Screening – Optimizing Tooth Cleaning Efficiency
Geozyme™ utilizes Artificial Intelligence (AI) to:
• Analyze over 20 million extremophile enzyme sequences
• Select the most optimized enzyme structure
As a result, the enzyme achieves:
• Precise protein degradation capability
• Superior tooth-cleaning performance
• Safe and selective activity
4. Enzymatic Mechanism – Breaking Down Protein Stains
Geozyme™ works like a “biological scissor,” cutting protein bonds responsible for tooth staining at a frequency of up to:
👉 317 times per second. Delivering deep cleaning without damaging or abrading tooth enamel.

5. Key Benefits:
Teeth Whitening Performance
• Model preparation method: Bovine teeth were acidified using phosphoric acid solution for 5 minutes, then immersed in a 2% Phycocyanin solution (blue microalgae pigment) for 2 days to create a protein-stain tooth model.
• Test results::
+ Initial condition: Teeth appeared blue due to pigment staining
+ After 5 minutes of shaking (with 4% Geozyme solution): Teeth became visibly lighter
+ After 1 hour: Teeth returned to their original white color, indicating complete degradation of the pigmented proteins
=> Geozyme™ breaks down the structure of protein-based stains, helping restore the natural whiteness of teeth safely and effectively.

6. Applications & Formulation Notes
• Recommended use level: 1–4%
• Appearance: Transparent liquid, water-soluble
• Applications: Oral care products (toothpaste, mouthwash, whitening serum/gel, etc.)
• Optimal pH range: 4–7
• Avoid use with strong oxidizing agents.





